The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2015

Filed:

Jun. 26, 2012
Applicants:

Jürgen Klar, Wuppertal, DE;

Verena Vöhringer, Wolfegg, DE;

Joachim Telser, Wuppertal, DE;

Mario Lobell, Wuppertal, DE;

Frank Süβmeier, München, DE;

Volkhart Min-jian LI, Velbert, DE;

Michael Böttger, Wuppertal, DE;

Stefan Golz, Mülheim an der Ruhr, DE;

Dieter Lang, Velbert, DE;

Karl-heinz Schlemmer, Wuppertal, DE;

Thomas Schlange, Haan, DE;

Andreas Schall, Wuppertal, DE;

Wenlang Fu, Florham Park, NJ (US);

Inventors:

Jürgen Klar, Wuppertal, DE;

Verena Vöhringer, Wolfegg, DE;

Joachim Telser, Wuppertal, DE;

Mario Lobell, Wuppertal, DE;

Frank Süβmeier, München, DE;

Volkhart Min-Jian Li, Velbert, DE;

Michael Böttger, Wuppertal, DE;

Stefan Golz, Mülheim an der Ruhr, DE;

Dieter Lang, Velbert, DE;

Karl-Heinz Schlemmer, Wuppertal, DE;

Thomas Schlange, Haan, DE;

Andreas Schall, Wuppertal, DE;

Wenlang Fu, Florham Park, NJ (US);

Assignee:
Attorney:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 401/04 (2006.01); A61K 31/53 (2006.01); A61K 31/4427 (2006.01); A61P 25/02 (2006.01); A61P 27/02 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/4427 (2013.01); C07D 401/04 (2013.01); C07D 487/04 (2013.01); A61K 31/53 (2013.01);
Abstract

This invention relates to novel 5-[(hydroxymethyl)aryl]-substituted pyrrolo[2,1-f][1,2,4]triazin-4-amines of formula (I), to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating angiogenesis-related disorders, in particular angiogenesis-related ocular disorders.


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