The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2015
Filed:
Sep. 20, 2012
Spago Imaging Ab, Stockholm, SE;
Oskar Axelsson, Höör, SE;
Rodrigo M. Petoral, Jr., Lund, SE;
Fredrik Ek, Lund, SE;
Petter Lauritzson, Hässleholm, SE;
SPAGO IMAGING AB, Stockholm, SE;
Abstract
Disclosed herein are nanostructures comprising a polymeric framework comprising at least five geminal bisphosphonate groups, wherein the geminal bisphosphonate groups independently of each other are incorporated as —RRC(P═O(OR)(OR)), wherein Rand Rare independently selected from the group consisting of a negative charge, H, alkyl and aryl, and wherein at least one of Rand Ris a group connected to the polymeric framework with the proviso that when only one of Rand Ris such a connected group, the other of Rand Ris either a group being able to connect to the polymeric framework, or the residue of such a group, or selected from the group consisting of H, OH, ORand R, wherein Ris a lower alkyl. The polymeric framework may comprise manganese ions. Disclosed are also methods for producing such manganese containing nanostructures, compositions comprising such manganese containing nanostructures and use of such manganese containing nanostructures, i.a. as MRI contrasting agents.