The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2015

Filed:

Dec. 13, 2013
Applicant:

Merck Patent Gmbh, Darmstadt, DE;

Inventors:

Amanda E. Sutton, Hingham, MA (US);

Thomas E. Richardson, Durham, NC (US);

Bayard R. Huck, Sudbury, MA (US);

Srinivasa R. Karra, Pembroke, MA (US);

Xiaoling Chen, Chestnut Hill, MA (US);

Yufang Xiao, Lexington, MA (US);

Andreas Goutopoulos, Boston, MA (US);

Ruoxi Lan, Waltham, MA (US);

David Perrey, Durham, NC (US);

Harold George Vandeveer, Indianapolis, IN (US);

Lesley Liu-Bujalski, Bedford, MA (US);

Frank Stieber, Einhausen, DE;

Brian L. Hodous, Cambridge, MA (US);

Hui Qiu, Acton, MA (US);

Reinaldo C. Jones, Lowell, MA (US);

Brian H. Heasley, Wake Forest, NC (US);

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/04 (2006.01); A61K 31/47 (2006.01); C07D 239/94 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 409/04 (2006.01); C07D 409/12 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
C07D 215/04 (2013.01); C07D 239/94 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 409/04 (2013.01); C07D 409/12 (2013.01); C07D 413/04 (2013.01); A61K 31/47 (2013.01);
Abstract

The invention provides novel substituted amino azaheterocyclic carboxamide compounds according to Formula (I), their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.


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