The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2015

Filed:

Dec. 04, 2012
Applicant:

Alkermes, Inc.;

Inventors:

Derrick Arnelle, Arlington, MA (US);

Daniel Deaver, Franklin, MA (US);

Reginald L. Dean, III, Boxborough, MA (US);

Mark Todtenkopf, Franklin, MA (US);

Assignee:

Alkermes, Inc., Waltham, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); A61K 45/06 (2006.01); C07D 221/28 (2006.01); C07D 489/00 (2006.01); C07D 489/08 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 489/08 (2013.01); A61K 31/485 (2013.01); A61K 45/06 (2013.01); C07D 471/08 (2013.01);
Abstract

The present invention relates to compounds of Formula I or II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which relates to mophinan compounds useful as μ, δ and/or κ receptor opioid compounds and pharmaceuticals containing same that may be useful for mediating analgesia, combating drug addiction, alcohol addiction, drug overdose, mental illness, bladder dysfunctions, neurogenic bladder, interstitial cystitis, urinary incontinence, premature ejaculation, inflammatory pain, peripherally mediated and neuropathic pain, cough, lung edema, diarrhea, cardiac disorders, cardioprotection, depression, and cognitive, respiratory, diarrhea, irritable bowel syndrome and gastro-intestinal disorders, immunomodulation, and anti-tumor agents.


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