The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2015

Filed:

Aug. 12, 2011
Applicants:

Kathryn Bell, London, GB;

Nelly Piton, Suffolk, GB;

Claudio Dagostin, Cambridge, GB;

Cyrille Boussard, Saffron Walden, GB;

Andrew Ratcliffe, Brentwood, GB;

Nigel Ramsden, Royston, GB;

Inventors:

Kathryn Bell, London, GB;

Nelly Piton, Suffolk, GB;

Claudio Dagostin, Cambridge, GB;

Cyrille Boussard, Saffron Walden, GB;

Andrew Ratcliffe, Brentwood, GB;

Nigel Ramsden, Royston, GB;

Assignee:

Cellzome Limited, Brentford, Middlesex, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); C07D 487/00 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01); C07D 491/107 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); C07D 519/00 (2013.01); C07D 491/107 (2013.01); C07D 498/08 (2013.01);
Abstract

The present invention relates to compounds of formula (I) wherein Xto X, Y, Zto Z, and R have the meaning as cited in the description and the claims. Said compounds are useful as JAK inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.


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