The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 26, 2015

Filed:

Jul. 31, 2012
Applicants:

Tomoya Shiro, Suita, JP;

Masanori Tobe, Suita, JP;

Katsumi Kubota, Osaka, JP;

Yosuke Takanashi, Osaka, JP;

Tomoaki Nakamura, Osaka, JP;

Toshihiko Sone, Osaka, JP;

Inventors:

Tomoya Shiro, Suita, JP;

Masanori Tobe, Suita, JP;

Katsumi Kubota, Osaka, JP;

Yosuke Takanashi, Osaka, JP;

Tomoaki Nakamura, Osaka, JP;

Toshihiko Sone, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); A61K 31/4015 (2006.01); A61K 31/497 (2006.01); A61K 31/535 (2006.01); A61K 31/54 (2006.01); C07D 401/04 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 403/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 401/04 (2013.01); C07D 403/14 (2013.01); C07D 409/14 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention provides: an uracil derivative represented by general formula (I) or a physiologically acceptable salt thereof (in the formula, Rrepresents a hydrogen atom, a Calkyl group, a Calkene group or a 3- to 6-membered saturated or 4- to 6-membered unsaturated aliphatic ring group which may contain 1 to 2 hetero atoms independently selected from the group consisting of N, O and S; Rrepresents a hydrogen atom, a halogen atom, a cyano group, —NRR, —N═CHN(CH), or an Calkyl group; Arand Arindependently represent a 5- to 6-membered aromatic ring group which may contain 1 to 3 hetero atoms independently selected from the group consisting of N, O and S; and L represents a 6-membered aromatic ring group which may contain 1 to 4 nitrogen atoms, a pyrazole group, a triazole group, or an imidazole group); and a therapeutic agent or prophylactic agent for various inflammatory diseases associated with elastase, comprises the compound or the like as an active ingredient.


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