The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2015
Filed:
Apr. 14, 2011
Sushmita Mimi Roy, Sunnyvale, CA (US);
Sunil Bajad, Fremont, CA (US);
Evan Green, Mountain View, CA (US);
Henry Heinsohn, Alameda, CA (US);
Sushmita Mimi Roy, Sunnyvale, CA (US);
Sunil Bajad, Fremont, CA (US);
Evan Green, Mountain View, CA (US);
Henry Heinsohn, Alameda, CA (US);
Sutro Biopharma, Inc., South San Francisco, CA (US);
Abstract
The present invention provides a method for monitoring of profile changes of components in a dynamic system such as a cell-free in vitro protein synthesis system by using liquid chromatography (LC) combined with mass spectrometry (MS). In an additional aspect, this invention provides a method for enhancing the yield and/or reproducibility in a cell-free protein synthesis system by modulating the level and/or activity of a protein component that has regulatory effects on the system.