The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2015
Filed:
Sep. 25, 2011
Cheng-hsun Chiu, Taoyuan, TW;
Rajendra Prasad Janapatla, Taoyuan, TW;
Chyi-liang Chen, Taoyuan, TW;
Mei-hua Hsu, Taoyuan, TW;
Hsiu-ling Chen, Taoyuan, TW;
Chung-tsui Huang, Taoyuan, TW;
Hsin-ju Chang, Taoyuan, TW;
Wan-ting Liao, Taoyuan, TW;
Cheng-Hsun Chiu, Taoyuan, TW;
Rajendra Prasad Janapatla, Taoyuan, TW;
Chyi-Liang Chen, Taoyuan, TW;
Mei-Hua Hsu, Taoyuan, TW;
Hsiu-Ling Chen, Taoyuan, TW;
Chung-Tsui Huang, Taoyuan, TW;
Hsin-Ju Chang, Taoyuan, TW;
Wan-Ting Liao, Taoyuan, TW;
CHANG GUNG MEDICAL FOUNDATION, LINKOU BRANCH, Taoyuan, TW;
Abstract
A method of providing protection against pneumococcal infection in a subject is disclosed. The method includes steps of administering to the subject a composition that includes combination of three recombinant pneumococcal neuraminidases: NanA, NanB, and NanC ofstrains CGSP14, wherein administration of the recombinant pneumococcal neuraminidases elicits an immune response to, and treats the subject. In one embodiment, the method further includes a step of adding adjuvants to enhance the immune response. The method also includes a step of using passive antibodies, wherein said passive antibodies are anti-neuraminidase antibodies generated from neuraminidases-immunized humanized animals: NanA, NanB, and NanC. Meanwhile, this invention also provides a method for the molecular diagnosis of pneumococcal infection.