The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2015
Filed:
Sep. 23, 2011
Mei-hui Wang, Taoyuan County, TW;
Wuu-jyh Lin, Taoyuan County, TW;
Hung-man Yu, Taoyuan County, TW;
Chuan-yi Chien, Taoyuan County, TW;
Ping-yen Wang, Taoyuan County, TW;
Mei-Hui Wang, Taoyuan County, TW;
Wuu-Jyh Lin, Taoyuan County, TW;
Hung-Man Yu, Taoyuan County, TW;
Chuan-Yi Chien, Taoyuan County, TW;
Ping-Yen Wang, Taoyuan County, TW;
INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, Taoyuan County, TW;
Abstract
The present invention is related to a pharmaceutical composition for a liver-receptor imaging injection, the pharmaceutical composition including a bi-functional compound which has a ASGPR specificity, wherein the bi-functional compound includes a backbone of alpha-amino acid (or the derivatives thereof) and a poly-galactosamine chain (or a poly-lactose chain) connected to the alpha-amino acid. Thereby, the pharmaceutical composition can quantify potential of liver storage ability and evaluate severity of the course of liver disease. A liver-receptor imaging injection using the same and the one-step dispensing method thereof are also provided to improve defects of iodine-labeled and overcome disadvantages of the reduced labeling-yield and the instability after autoclave sterilization.