The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 26, 2015
Filed:
Apr. 18, 2014
Applicant:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Inventors:
Anthony Atala, Winston-Salem, NC (US);
James J. Yoo, Winston-Salem, NC (US);
Grace Lim, Winston-Salem, NC (US);
Sang Jin Lee, Winston-Salem, NC (US);
Assignee:
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/28 (2006.01); A61K 38/18 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/48 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01); A61K 35/32 (2006.01); A61K 35/34 (2006.01);
U.S. Cl.
CPC ...
A61F 2/28 (2013.01); A61K 38/18 (2013.01); A61L 27/3604 (2013.01); A61L 27/3817 (2013.01); A61L 27/3821 (2013.01); A61L 27/3826 (2013.01); A61L 27/383 (2013.01); A61L 27/3891 (2013.01); A61L 27/48 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61K 35/32 (2013.01); A61K 35/34 (2013.01); A61L 2430/02 (2013.01);
Abstract
The invention pertains to methods of producing artificial composite tissue constructs that permit coordinated motion. Biocompatable structural matrices having sufficient rigidity to provide structural support for cartilage-forming cells and bone-forming cells are used. Biocompatable flexible matrices seeded with muscle cells are joined to the structural matrices to produce artificial composite tissue constructs that are capable of coordinated motion.