The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2015

Filed:

Apr. 21, 2011
Applicants:

Daniel T. Belmont, Grafton, MA (US);

Cristian Harrison, Beveryly, MA (US);

Robert Michael Hughes, San Diego, CA (US);

Young Chun Jung, Lexington, MA (US);

Elaine Chungmin Lee, Arlington, MA (US);

Benjamin Joseph Littler, Carlsbad, CA (US);

Peter Jamison Rose, Littleton, MA (US);

David Andrew Siesel, San Diego, CA (US);

Gerald J. Tanoury, Marlborough, MA (US);

Inventors:

Daniel T. Belmont, Grafton, MA (US);

Cristian Harrison, Beveryly, MA (US);

Robert Michael Hughes, San Diego, CA (US);

Young Chun Jung, Lexington, MA (US);

Elaine Chungmin Lee, Arlington, MA (US);

Benjamin Joseph Littler, Carlsbad, CA (US);

Peter Jamison Rose, Littleton, MA (US);

David Andrew Siesel, San Diego, CA (US);

Gerald J. Tanoury, Marlborough, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/40 (2006.01); C07D 405/12 (2006.01); C07D 209/12 (2006.01); C07D 317/46 (2006.01); C07D 317/60 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); C07D 209/12 (2013.01); C07D 317/46 (2013.01); C07D 317/60 (2013.01);
Abstract

The present invention features processes for preparing compounds, such as (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1), useful for treating CFTR mediated diseases such as cystic fibrosis.


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