The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
Dec. 11, 2009
Daniel Cravo, Montesson, FR;
Sophie Hallakou-bozec, Montrouge, FR;
Didier Mesangeau, Combs la Ville, FR;
Samer Elbawab, Bures sur Yvette, FR;
Daniel Cravo, Montesson, FR;
Sophie Hallakou-Bozec, Montrouge, FR;
Didier Mesangeau, Combs la Ville, FR;
Samer Elbawab, Bures sur Yvette, FR;
POXEL, Lyons, FR;
Abstract
The invention relates to compounds of formula (I) wherein the radicals Rto Rhave the meaning according to claim, and/or physiologically acceptable salts thereof, for the prophylactic or therapeutic treatment and/or monitoring of physiological and/or pathological conditions that are associated with the activity of AMP-activated protein kinase (AMPK). Another object of the invention concerns the use of said compounds for enhancing glucose homeostasis, improving podocytopathy and/or decreasing the production of reactive oxygen species (ROS). The invention also relates to a method for in-vitro diagnosing diabetic nephropathy and a method for screening compounds that reduce podocytopathy, in each case by applying synaptopodin as biomarker.