The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
Mar. 08, 2011
Elliot L. Chaikof, Atlanta, GA (US);
Karlheinz Peter, Hawthorne East, AU;
Danijal Topcic, Highett, AU;
Carolyn A. Haller, Wellesley, MA (US);
Wookhyun Kim, Boston, MA (US);
Elliot L. Chaikof, Atlanta, GA (US);
Karlheinz Peter, Hawthorne East, AU;
Danijal Topcic, Highett, AU;
Carolyn A. Haller, Wellesley, MA (US);
Wookhyun Kim, Boston, MA (US);
Emory University, Atlanta, GA (US);
Baker IDI Heart & Diabetes Institute Holdings Ltd., Melbourne, AU;
Abstract
This disclosure relates to temperature sensitive conjugates, compositions, and uses related thereto. In certain embodiments, the disclosure relates to conjugate polymers comprising a) a temperature sensitive polymer and b) an antibody. Typically the antibody has an epitope to a platelet receptor. The antibody may be a single-chain antibody wherein the platelet receptor is GPIIb/IIIa, such as an anti-GPIIb/IIIa antibody. In certain embodiments, the antibody binds specifically to the activated conformation of GPIIb/IIIa, i.e., an activation-specific GPIIb/IIIa antibody.