The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
May. 26, 2006
Karin Hoffmann, Schwetzingen, DE;
Sergey Kipriyanov, Heidelberg, DE;
Stefan Knackmuss, Plankstadt, DE;
Fabrice Le Gall, Edingen-Neckarhausen, DE;
Melvyn Little, Neckargemünd, DE;
Uwe Reusch, Maikammer, DE;
Karin Hoffmann, Schwetzingen, DE;
Sergey Kipriyanov, Heidelberg, DE;
Stefan Knackmuss, Plankstadt, DE;
Fabrice Le Gall, Edingen-Neckarhausen, DE;
Melvyn Little, Neckargemünd, DE;
Uwe Reusch, Maikammer, DE;
Affimed GMBH, Heidelberg, DE;
Abstract
The present invention relates to binding molecules that specifically bind to the human Fc gamma receptor expressed on the surface of natural killer (NK) cells and macrophages (i.e. FcγRIIIA), and in particular binding molecules that specifically bind the A form FcγRIII but do not bind to the B form of FcγRIII, as well as to the use of such binding molecules in the diagnosis and treatment of disease. The invention further extends to polynucleotides encoding such binding molecules, host cells comprising such polynucleotides and methods of producing binding molecules of the invention using such host cells.