The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
Oct. 17, 2014
Applicant:
Quanticel Pharmaceuticals, San Diego, CA (US);
Inventors:
Michael John Bennett, San Diego, CA (US);
Juan Manuel Betancort, San Diego, CA (US);
Amogh Boloor, San Diego, CA (US);
Stephen W. Kaldor, San Diego, CA (US);
Jeffrey Alan Stafford, San Diego, CA (US);
James Marvin Veal, Apex, NC (US);
Assignee:
Quanticel Pharmaceuticals, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); C07D 217/24 (2006.01); C07D 498/04 (2006.01); C07D 413/04 (2006.01); C07D 401/04 (2006.01); C07D 471/04 (2006.01); C07D 405/04 (2006.01); C07D 487/04 (2006.01); C07D 211/94 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07D 217/24 (2013.01); C07D 413/04 (2013.01); C07D 401/04 (2013.01); C07D 471/04 (2013.01); C07D 405/04 (2013.01); C07D 487/04 (2013.01); C07D 211/94 (2013.01);
Abstract
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.