The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
Mar. 06, 2014
Applicants:
Purdue Research Foundation, West Lafayette, IN (US);
United States Government National Institutes of Health (Nih), U.s. Dept. of Health and Human Services (Dhhs), Washington, DC (US);
Inventors:
Mark S. Cushman, West Lafayette, IN (US);
Evgeny A. Kiselev, Silver Spring, MD (US);
Andrew E. Morrell, San Diego, CA (US);
Yves George Pommier, Bethesda, MD (US);
Assignees:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract
The invention described herein pertains to substituted azaindenoisoquinoline compounds, in particular 7-, 8-, 9-, and 10-azaindenoisoquinoline compounds, which are inhibitors of topoisomerase I, processes and intermediates for their syntheses, pharmaceutical compositions of the compounds, and methods of using them in the treatment of cancer.