The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
Nov. 30, 2012
Applicant:
Fibrogen, Inc., San Francisco, CA (US);
Inventors:
Al Y. Lin, San Francisco, CA (US);
Thomas B. Neff, San Francisco, CA (US);
Noelynn A. Oliver, Ridgefield, CT (US);
William R. Usinger, Lafayette, CA (US);
Qingjian Wang, Belmont, CA (US);
David A. Yeowell, San Francisco, CA (US);
Assignee:
FibroGen, Inc., San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 15/12 (2006.01); C12N 5/12 (2006.01); C12N 15/13 (2006.01); C12N 5/10 (2006.01); C07H 21/04 (2006.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 2039/505 (2013.01); C07K 2316/96 (2013.01);
Abstract
The present invention relates to antibodies that bind to CTGF. The antibodies are particularly directed to regions of CTGF involved in biological activities associated with fibrosis. The invention also relates to methods of using the antibodies to treat disorders associated with CTGF including localized and systemic fibrotic disorders including those of the lung, liver, heart, skin, and kidney.