The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2015

Filed:

Jan. 09, 2014
Applicant:

Nationwide Children's Hospital, Inc., Columbus, OH (US);

Inventors:

Lauren O. Bakaletz, Hilliard, OH (US);

Robert S. Munson, Jr., Columbus, OH (US);

David W. Dyer, Oklahoma City, OK (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C07K 16/12 (2006.01); C07K 14/285 (2006.01); A61K 39/102 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1242 (2013.01); A61K 39/00 (2013.01); C07K 14/285 (2013.01); A61K 39/102 (2013.01);
Abstract

The invention relates to the polynucleotide sequence of a nontypeable strain of(NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also relates to NTHi genes which are upregulated during or in response to NTHi infection of the middle ear and/or the nasopharynx.


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