The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
Jun. 05, 2014
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Centre National DE LA Recherche Scientifique—cnrs, Paris, FR;
Universite DE LA Mediterranee—aix-marseille Ii, Marseilles, FR;
Universidad DE Navarra, Pamplona, ES;
Jean-Pierre Gorvel, Marseille Cedex, FR;
Vilma Arce Gorvel, Marseille Cedex, FR;
Maite Iriarte, Pamplona, ES;
Ignacio Moriyon, Pamplona, ES;
Raquel Conde-Alvarez, Pamplona, ES;
Institut National de la Sante et de la Recherche Medicale (INSERM), Paris, FR;
Centre National de la Recherche Scientifique—CNRS, Paris, FR;
Université d'Aix Marseille, Marseilles, FR;
UNIVERSIDAD DE NAVARRA, Pamplona, ES;
Abstract
The invention relates to Gram-negative bacteria carrying an inactivated gene encoding a glycosyltransferase involved in the synthesis of the core of the LPS of said Gram-negative bacteria, wherein said inactivated gene results in the synthesis of a LPS having a modified core. These strains have an attenuated virulence but induce a humoral immunity sufficient for ensuring vaccination of the host.