The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 19, 2015
Filed:
Sep. 21, 2010
Applicants:
Zeev Smilansky, M.P. Emek Soreq, IL;
Barry S. Cooperman, Penn Valley, PA (US);
Yale E. Goodman, Merion, PA (US);
Inventors:
Zeev Smilansky, M.P. Emek Soreq, IL;
Barry S. Cooperman, Penn Valley, PA (US);
Yale E. Goodman, Merion, PA (US);
Assignee:
ANIMA CELL METROLOGY INC., Bernardsville, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/50 (2006.01); G01N 33/542 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5023 (2013.01); G01N 33/542 (2013.01);
Abstract
The present invention relates to systems and methods for measuring the rate of translation of a target protein in cells, which are based on the detection of translation of one or more predetermined codon pairs during synthesis of the target protein. The detection is provided by a FRET signal emitted from labeled tRNA molecules which are juxtaposed during synthesis of the protein.