The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2015

Filed:

Jun. 05, 2014
Applicant:

Shanghai Zerun Biotechnology Co., Ltd., Shanghai, CN;

Inventors:

Goaxia Zhang, Shanghai, CN;

Qiong Shen, Shanghai, CN;

Jianqiang Lei, Shanghai, CN;

Jingyu Yuan, Shanghai, CN;

Menghua Zhang, Shanghai, CN;

Qianli Zhang, Shanghai, CN;

Yinghua Xiong, Shanghai, CN;

Roger Wei, Shanghai, CN;

Ke Wu, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); C12N 15/81 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); Y10T 428/2982 (2015.01); A61K 39/12 (2013.01); C12N 7/00 (2013.01); C12N 15/81 (2013.01); C12N 2710/18022 (2013.01); C12N 2710/20022 (2013.01); C12N 2710/20023 (2013.01); C12N 2710/20034 (2013.01);
Abstract

The present invention discloses a codon-optimized gene encoding major capsid protein L1 of human papilloma virus, which is capable, after transduced into a yeast cell, of efficiently expressing the major capsid protein L1 of human papilloma virus. The present invention also discloses an immunogenic macromolecule which is essentially produced by expression of said codon-optimized gene encoding the major capsid protein L1 of human papilloma virus in a yeast cell. The present invention further discloses the use of said immunogenic macromolecule and a composition comprising said immunogenic macromolecule.


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