The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2015

Filed:

Aug. 26, 2011
Applicants:

Pär Gellerfors, Lidingö, SE;

Lars Lannfelt, Stockholm, SE;

Dag Sehlin, Uppsala, SE;

Frida Ekholm Pettersson, Uppsala, SE;

Hillevi Englund, Uppsala, SE;

Inventors:

Pär Gellerfors, Lidingö, SE;

Lars Lannfelt, Stockholm, SE;

Dag Sehlin, Uppsala, SE;

Frida Ekholm Pettersson, Uppsala, SE;

Hillevi Englund, Uppsala, SE;

Assignee:

BioArctic Neuroscience AB, Stockholm, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); G01N 33/68 (2006.01); C07K 16/18 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); A61K 2039/505 (2013.01); C07K 16/18 (2013.01); C07K 16/465 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); G01N 2333/4709 (2013.01); G01N 2800/2814 (2013.01); G01N 2800/387 (2013.01);
Abstract

The invention relates to an isolated antibody, or fragment thereof, having high affinity for human Aβ protofibrils. The invention further relates to compositions that include the antibody, or a fragment thereof, and a pharmaceutically acceptable buffer. The invention further relates to a method of preventing or treating Alzheimer's disease, which includes the step of administering to a patient having or suspected of having Alzheimer's disease such an antibody, or fragment thereof or a composition that includes the antibody or a fragment thereof.


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