The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 19, 2015

Filed:

Jun. 06, 2012
Applicants:

Scott M. Husson, Greenville, SC (US);

Bharat V. Bhut, Jamesville, MN (US);

Inventors:

Scott M. Husson, Greenville, SC (US);

Bharat V. Bhut, Jamesville, MN (US);

Assignee:

Clemson University, Clemson, SC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 39/00 (2006.01); B01D 39/14 (2006.01); B01D 67/00 (2006.01); B01D 71/06 (2006.01); B01D 71/10 (2006.01); B29C 44/04 (2006.01); B01D 71/34 (2006.01); B01D 71/82 (2006.01);
U.S. Cl.
CPC ...
B01D 71/34 (2013.01); B01D 71/82 (2013.01);
Abstract

Processes for preparation of macroporous membranes having unusually high equilibrium protein binding capacities are described. Membranes include a self-supporting porous membrane substrate and a grafted polymeric film on the pore surfaces of the substrate. A polymeric film may be grafted to the porous membrane substrate using surface-initiated polymerization. The grafted polymer chains within the polymeric film can act as molecular 'brushes' or 'tentacles' in solution and can contain one or more capture chemistries for biomolecules. Membranes can be used in the separation and purification of biomolecules such as proteins, nucleic acids, virus or virus-like particles, endotoxins, and the like.


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