The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2015

Filed:

Dec. 29, 2006
Applicant:

Richard J. Knox, Carmarthen, GB;

Inventor:

Richard J. Knox, Carmarthen, GB;

Assignee:

Morvus Technology Limited, Carmarthen, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 203/14 (2006.01); C07B 31/00 (2006.01); A61K 31/04 (2006.01); A61K 31/045 (2006.01); A61K 31/12 (2006.01); A61K 31/396 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/04 (2013.01); C07D 203/14 (2013.01); C07B 31/00 (2013.01); A61K 31/045 (2013.01); A61K 31/12 (2013.01); A61K 31/396 (2013.01); A61K 45/06 (2013.01);
Abstract

There is provided the use as reducing agents of alpha-hydroxycarbonyl compounds capable of forming cyclic dimers. There is also provided corresponding methods of reducing reducible compounds, particularly reduction-activated prodrugs. Examples of the alpha-hydroxycarbonyl compounds used are dihydroxyacetone, glycolaldehyde, glyceraldehyde, erythrose, xylulose, erythrulose or 3-hydroxy-2-butanone.


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