The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2015
Filed:
Jul. 27, 2011
David Yavorsky, Bolton, MA (US);
John Amara, Reading, MA (US);
Joaquin Umana, Stoneham, MA (US);
William Cataldo, Bradford, MA (US);
Mikhail Kozlov, Lexington, MA (US);
Matthew Stone, Cambridge, MA (US);
David Yavorsky, Bolton, MA (US);
John Amara, Reading, MA (US);
Joaquin Umana, Stoneham, MA (US);
William Cataldo, Bradford, MA (US);
Mikhail Kozlov, Lexington, MA (US);
Matthew Stone, Cambridge, MA (US);
EMD Millipore Corporation, Billerica, MA (US);
Abstract
Adsorptive media for chromatography, particularly ion-exchange chromatography, derived from a shaped fiber. In certain embodiments, the functionalized shaped fiber presents a fibrillated or ridged structure which greatly increases the surface area of the fibers when compared to ordinary fibers. Also disclosed herein is a method to add surface pendant functional groups that provides cation-exchange or anion-exchange functionality to the high surface area fibers. This pendant functionality is useful for the ion-exchange chromatographic purification of biomolecules, such as monoclonal antibodies (mAbs).