The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2015
Filed:
Aug. 31, 2011
Aya Jakobovits, Beverly Hills, CA (US);
Soudabeh Etessami, Tarzana, CA (US);
Pia M. Challita-eid, Encino, CA (US);
Juan J. Perez-villar, Los Angeles, CA (US);
Karen J. Morrison, Santa Monica, CA (US);
Xiao-chi Jia, Los Angeles, CA (US);
Mary Faris, Los Angeles, CA (US);
Jean Gudas, Pacific Palisades, CA (US);
Arthur B. Raitano, Los Angeles, CA (US);
Aya Jakobovits, Beverly Hills, CA (US);
Soudabeh Etessami, Tarzana, CA (US);
Pia M. Challita-Eid, Encino, CA (US);
Juan J. Perez-Villar, Los Angeles, CA (US);
Karen J. Morrison, Santa Monica, CA (US);
Xiao-Chi Jia, Los Angeles, CA (US);
Mary Faris, Los Angeles, CA (US);
Jean Gudas, Pacific Palisades, CA (US);
Arthur B. Raitano, Los Angeles, CA (US);
Agensys, Inc., Santa Monica, CA (US);
Abstract
Antibodies and molecules derived therefrom that bind to novel STEAP-1 protein, and variants thereof, are described wherein STEAP-1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, STEAP-1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The STEAP-1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with STEAP-1 can be used in active or passive immunization.