The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2015

Filed:

Sep. 17, 2013
Applicant:

Board of Regents of the University of Texas System, Austin, TX (US);

Inventors:

Kenneth Michael Hargreaves, San Antonio, TX (US);

John Gordon Bruno, Boerne, TX (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); A61K 47/48092 (2013.01); C12N 2310/16 (2013.01); C12N 2310/351 (2013.01); C12N 2310/3519 (2013.01);
Abstract

A method for treating and/or diagnosing pain and the source or type of pain, shock, and/or inflammatory conditions in a subject. A method of using a therapeutically effective amount of a DNA or RNA aptamer that shows high affinity for OLAMs to at least partially treat pain, shock, and/or inflammatory conditions in a subject. The DNA or RNA aptamer that shows high affinity for OLAMs may be coupled to a plasma protein binding compound or a pharmacologically active agent. A method of treating and or diagnosing pain, shock, and/or inflammatory conditions in a subject may include inactivating or preventing at least one linoleic acid metabolite to treat certain conditions (e.g., pain, shock, and/or inflammation) using a DNA or RNA aptamer that shows high affinity for OLAMs.


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