The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2015

Filed:

Dec. 15, 2011
Applicants:

Qing Lin, Getzville, NY (US);

Avinash Muppidi, Buffalo, NY (US);

Inventors:

Qing Lin, Getzville, NY (US);

Avinash Muppidi, Buffalo, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); C07K 7/56 (2006.01); C07K 1/107 (2006.01); C07K 7/08 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 7/56 (2013.01); C07K 1/1077 (2013.01); C07K 7/08 (2013.01); C07K 14/4747 (2013.01); C07K 2319/95 (2013.01); C07K 2319/00 (2013.01);
Abstract

Cross-linked proteins and peptides, and methods of making and uses of such cross-linked proteins and peptides. The cross-linked proteins and peptides have rigid, distance-matching bismethylene aryl cross-linking moieties. Compositions comprising the cross-linked proteins and peptides can be used as pharmaceutical delivery formulations. The cross-linked proteins and peptides can have improved properties, such as cell permeability, as compared to the parent protein or peptide.


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