The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9029133 B1

PDF
Full Text
Expired
Date of Patent:
May. 12, 2015

Filed:

Apr. 29, 2004
Applicants:

Qijun Qian, Shanghai, CN;

Qi Zhang, Shanghai, CN;

Qin Yang, Shanghai, CN;

Mengchao Wu, Shanghai, CN;

Inventors:

Qijun Qian, Shanghai, CN;

Qi Zhang, Shanghai, CN;

Qin Yang, Shanghai, CN;

Mengchao Wu, Shanghai, CN;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/861 (2006.01); A61K 39/235 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 35/13 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C12N 15/86 (2013.01); C12N 2710/10343 (2013.01); C12N 2750/14143 (2013.01);
Abstract

The present invention provides a recombinant virus containing a nucleotide sequence encoding a tumor-therapeutic full-length antibody with human constant regions, and uses thereof. After a nucleotide sequence of a gene encoding a tumor-therapeutic full-length antibody with human constant regions of the light chain and the heavy chain is inserted into the genome of a recombinant virus, the tumor-therapeutic full-length antibody with human constant regions can be efficiently expressed in tumor cells, thereby inhibit the growth and metastasis of tumors.


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