The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2015

Filed:

Feb. 26, 2010
Applicants:

Hashem Akhavan-tafti, Howell, MI (US);

Dean G. Binger, Saint Louis Park, MN (US);

Ying Chen, Eden Prairie, MN (US);

Renuka DE Silva, Northville, MI (US);

Terri Mclernon, Mounds View, MN (US);

James Mendoza, Robbinsdale, MN (US);

Bruce H. Odegaard, Crystal, MN (US);

Michael Salvati, Minnetrista, MN (US);

Nir Shapir, Falcon Heights, MN (US);

Wenhua Xie, Novi, MI (US);

Inventors:

Hashem Akhavan-Tafti, Howell, MI (US);

Dean G. Binger, Saint Louis Park, MN (US);

Ying Chen, Eden Prairie, MN (US);

Renuka De Silva, Northville, MI (US);

Terri McLernon, Mounds View, MN (US);

James Mendoza, Robbinsdale, MN (US);

Bruce H. Odegaard, Crystal, MN (US);

Michael Salvati, Minnetrista, MN (US);

Nir Shapir, Falcon Heights, MN (US);

Wenhua Xie, Novi, MI (US);

Assignee:

Beckman Coulter, Inc., Brea, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 30/00 (2006.01); C12Q 1/28 (2006.01); G01N 33/542 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/28 (2013.01); G01N 33/542 (2013.01); G01N 33/582 (2013.01);
Abstract

Methods, reagents, kits and systems are disclosed for determining an analyte in a sample suspected of containing the analyte where all reagents are soluble in aqueous solution. One assay method includes treating a sample suspected of containing the analyte under conditions such that if the analyte is present, an activator is brought into reactive configuration with a chemiluminescent compound to activates it. The sample is also treated with an agent to reduce signal not related to analyte. Finally, the sample is treated with a trigger solution thereby producing light from the activated chemiluminescent compound. No reagents are associated with a surface or other solid phase.


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