The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2015

Filed:

Oct. 16, 2012
Applicant:

Symphogen A/s, Lyngby, DK;

Inventors:

Lone Kjær Rasmussen, Skodsborg, DK;

Torben Frandsen, Frederiksberg, DK;

Søren Kofoed Rasmussen, Roskilde, DK;

Peter Sejer Andersen, Vanløse, DK;

Assignee:

Symphogen A/S, Lyngby, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/68 (2006.01); G01N 30/96 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); G01N 33/6803 (2013.01); G01N 30/96 (2013.01);
Abstract

The present invention provides a structural characterization platform that can be used to assess the stability of a polyclonal cell line during production, as well as batch-to-batch consistency of the final polyclonal products. The structural characterization platform is based on genetic analysis as well as protein characterization techniques that alone or in combination provides the necessary information to characterize the polyclonal cell line and final products. The collection of different homologous proteins to be analyzed with the platform techniques is for example a recombinant polyclonal antibody or a mixture of monoclonal antibodies.


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