The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 12, 2015

Filed:

Aug. 31, 2011
Applicants:

Eun Byul Kwon, Daejeon, KR;

Bong-sik Jeon, Daejeon, KR;

Eung Gyu Kim, Daejeon, KR;

Ju Young Park, Daejeon, KR;

Wan Jae Myeong, Daejeon, KR;

Inventors:

Eun Byul Kwon, Daejeon, KR;

Bong-Sik Jeon, Daejeon, KR;

Eung Gyu Kim, Daejeon, KR;

Ju Young Park, Daejeon, KR;

Wan Jae Myeong, Daejeon, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61K 49/18 (2006.01); A61K 49/12 (2006.01); B82Y 5/00 (2011.01); B01J 13/06 (2006.01);
U.S. Cl.
CPC ...
A61K 49/1863 (2013.01); A61K 49/128 (2013.01); A61K 49/1851 (2013.01); A61K 49/1818 (2013.01); A61K 49/1827 (2013.01); A61K 49/12 (2013.01); A61K 49/126 (2013.01); B82Y 5/00 (2013.01); B01J 13/06 (2013.01);
Abstract

Provided is an iron oxide nanocapsule which has extremely excellent water dispersibility, which is very stable in the body and which has very excellent MRI contrast ability, a method of manufacturing the same, and an MRI contrast agent using the same. The method of manufacturing the iron oxide nanocapsule includes the steps of: thermally decomposing an iron complex to prepare hydrophobic ligand-bonded iron oxide nanoparticles; and encapsulating the hydrophobic ligand-bonded iron oxide nanoparticles by a carboxymethyldextrandodecylamine conjugate encapsulation material or a dextran-linoleic acid conjugate encapsulation material to form an iron oxide nanocapsule.


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