The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2015
Filed:
Mar. 25, 2011
Applicants:
Yanwen Jin, Beijing, CN;
David Weaver, Newton, MA (US);
Michael Rynkiewicz, Newton, MA (US);
Cheng Cao, Beijing, CN;
Inventors:
Yanwen Jin, Beijing, CN;
David Weaver, Newton, MA (US);
Michael Rynkiewicz, Newton, MA (US);
Cheng Cao, Beijing, CN;
Assignee:
HeFei Tairui Biotechnology Co., Ltd., HeFei, AnHui Province, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61K 39/395 (2006.01); C07K 16/30 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); C07K 16/2863 (2013.01); C07K 2317/24 (2013.01); C07K 2317/92 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01);
Abstract
A humanized anti-EGFR antibody L4-H3 and gene encoding the antibody are disclosed. The antibody is composed of a heavy chain and a light chain. The amino acid sequence of the heavy chain variable region is shown as positions 1-145 of SEQ ID NO: 3, the heavy chain constant region is the heavy chain constant region of the human antibody IgG1, and the amino acid sequence of the light chain is shown as SEQ ID NO: 1.