The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2015
Filed:
Feb. 24, 2012
Applicants:
William A. Maltese, Toledo, OH (US);
Paul W. Erhardt, Toledo, OH (US);
Michael W. Robinson, Toledo, OH (US);
Jean H. Overmeyer, Perrysburg, OH (US);
Inventors:
William A. Maltese, Toledo, OH (US);
Paul W. Erhardt, Toledo, OH (US);
Michael W. Robinson, Toledo, OH (US);
Jean H. Overmeyer, Perrysburg, OH (US);
Assignee:
The University of Toledo, Toledo, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/06 (2006.01); A61K 45/06 (2006.01); A61K 31/4439 (2006.01); A61K 31/404 (2006.01); C07D 403/06 (2006.01); C07D 209/08 (2006.01); C07D 209/12 (2006.01); C40B 40/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/404 (2013.01); A61K 45/06 (2013.01); A61K 31/4439 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 209/08 (2013.01); C07D 209/12 (2013.01); C40B 40/04 (2013.01);
Abstract
The present invention provides materials and methods to induce cell death by methuosis, a non-apoptotic cell death mechanism. Small molecules herein are useful for treating cell proliferation disorders or anomalies, particularly, but not exclusively, cancer. Methods related to the research and pharmaceutical use of the small molecules are also provided herein.