The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2015
Filed:
Mar. 27, 2012
Applicants:
Antal Friesz, Budapest, HU;
Csaba Huszar, Budapest, HU;
Inventors:
Antal Friesz, Budapest, HU;
Csaba Huszar, Budapest, HU;
Assignee:
Sanofi, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 307/00 (2006.01); C07D 307/81 (2006.01); C07D 307/85 (2006.01); C07D 307/83 (2006.01);
U.S. Cl.
CPC ...
C07D 307/81 (2013.01); C07D 307/85 (2013.01); C07D 307/83 (2013.01);
Abstract
The invention relates to a novel process for preparation of drohedarone of formula (I) and pharmaceutically acceptable salts thereof characterized in that a compound of formula (II) is reacted in the presence of a reductive agent with butyraldehyde and/or butanoic acid, and isolating the obtained product and, if desired, converting it into a pharmaceutically acceptable salt thereof. The invention also relates to some hovel intermediary compounds and the preparation thereof.