The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2015
Filed:
Jul. 22, 2013
Atomic Energy Council—institute of Nuclear Energy Research, Taoyuan County, TW;
Show-Wen Liu, Taoyuan County, TW;
Yu Chang, Taoyuan County, TW;
Cheng-Fang Hsu, Taoyuan County, TW;
Sheng-Lun Lin, Taoyuan County, TW;
Tsung-Hsien Chiang, Taoyuan County, TW;
Chih-Yuan Lin, Taoyuan County, TW;
Atomic Energy Council—Institute of Nuclear Energy Research, Taoyuan County, TW;
Abstract
The present invention relates to a radiotracer precursor for imaging of hypoxic tissues, a radiotracer and a method for preparing the same. The radiotracer precursor, BANI, includes a nitroimidazole functional group with a feature of retention in hypoxic tissues and a bifunctional ligand able to complex with radioisotopes. Thus BANI can be used to produce radiotracers retained in hypoxic tissues and the radiotracers are applied to medical imaging of malignant tumor with hypoxic layer.