The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2015

Filed:

Jun. 23, 2010
Applicants:

Marc Geoffery Hummersone, Nottingham, GB;

Malcolm Francis Graham Stevens, Nottingham, GB;

David Cousin, Nottingham, GB;

Inventors:

Marc Geoffery Hummersone, Nottingham, GB;

Malcolm Francis Graham Stevens, Nottingham, GB;

David Cousin, Nottingham, GB;

Assignee:

Pharminox Limited, Nottingham, GB;

Attorney:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); A61K 31/4188 (2006.01); A61K 31/427 (2006.01); A61P 35/00 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07C 2101/02 (2013.01);
Abstract

The present invention pertains generally to the field of therapeutic compounds, and more specifically to 3-substituted-8-substituted-3H-imidazo[5,1-d][1,2,3,5]tetrazin-4-one compounds of the following formula, wherein -A and —B are as defined herein (collectively referred to herein as 38TM compounds): The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative disorders such as cancer, etc., and methods of preparing such compounds.


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