The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2015

Filed:

Jun. 30, 2009
Applicants:

Katsuhiro Mori, Tokyo, JP;

Naoko Hiura, Tokyo, JP;

Tsuguo Kubota, Tokyo, JP;

Akiko Furuya, Tokyo, JP;

Yutaka Kanda, Tokyo, JP;

Mitsuo Satoh, Tokyo, JP;

Inventors:

Katsuhiro Mori, Tokyo, JP;

Naoko Hiura, Tokyo, JP;

Tsuguo Kubota, Tokyo, JP;

Akiko Furuya, Tokyo, JP;

Yutaka Kanda, Tokyo, JP;

Mitsuo Satoh, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 19/00 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01); C07K 16/28 (2006.01); C12R 1/91 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57484 (2013.01); C07K 16/2878 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/734 (2013.01); C07K 2317/92 (2013.01); C12R 1/91 (2013.01); G01N 33/6863 (2013.01); G01N 2333/70578 (2013.01); G01N 2400/02 (2013.01); G01N 2800/347 (2013.01);
Abstract

The present invention provides a monoclonal antibody which specifically recognizes CD27 containing an O-linked sugar chain to which galactose is not bound and binds to its extracellular region, or a method for using the same. The present invention can provide a monoclonal antibody or an antibody fragment thereof, which specifically recognizes a polypeptide encoded by CD27 gene containing an O-linked sugar chain to which galactose is not bound, and binds to its extracellular region; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which comprises the DNA; a transformant obtainable by transforming the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a diagnostic agent or a therapeutic agent comprising the antibody or the antibody fragment thereof as an active ingredient.


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