The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2015

Filed:

Mar. 08, 2013
Applicant:

Natrogen Therapeutics International Inc., New York, NY (US);

Inventors:

Longgui Wang, Flushing, NY (US);

Xiao Mei Liu, Flushing, NY (US);

Lian Mo, Palo Alto, CA (US);

Simon K. Mencher, New York, NY (US);

James P. McCarron, Jr., New York, NY (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/38 (2006.01); A61K 31/40 (2006.01); A01N 43/12 (2006.01); A61K 31/38 (2006.01); A01N 43/06 (2006.01); A61K 31/105 (2006.01); A61K 31/404 (2006.01); A61K 31/7056 (2006.01); A61K 45/06 (2006.01); A61K 45/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/404 (2013.01); A61K 31/7056 (2013.01); A61K 45/06 (2013.01); A61K 45/00 (2013.01);
Abstract

The invention relates to pharmaceutical compositions and methods of treating inflammatory-related diseases associated with pro-inflammatory cytokine expression and/or reduced expression of anti-inflammatory cytokines. The method typically comprises administration of one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, such as, Meisoindigo and NATURA. Preferably the pharmaceutical composition comprises one or more compounds selected from isoindigo, indigo, indirubin, or derivatives thereof, an anti-inflammatory agent, and a pharmaceutically acceptable carrier.


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