The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2015
Filed:
Oct. 14, 2010
Applicant:
Vineet Gupta, Pinecrest, FL (US);
Inventor:
Vineet Gupta, Pinecrest, FL (US);
Assignee:
Adhaere Pharmaceuticals, Inc., Miami, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/34 (2006.01); C07D 277/36 (2006.01); A61K 31/425 (2006.01); C07D 417/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/06 (2013.01);
Abstract
The application describes small molecules capable of modulating activity of beta2 family of integrins, such as integrin CD11b/CD18 (also known as Mac-1, CR3 and αMβ2). Such compounds may be used in certain embodiments for treating a disease or condition, such as inflammation, immune-related disorders, cancer, ischemia-reperfusion injury, stroke, neointimal thickening associated with vascular injury, wound-healing, organ transplantation and cardiovascular disease, among others.