The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2015
Filed:
Dec. 06, 2010
Applicants:
Claudio Pisano, Aprilia, IT;
Loredana Vesci, Rome, IT;
Inventors:
Claudio Pisano, Aprilia, IT;
Loredana Vesci, Rome, IT;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/24 (2006.01); A61K 31/335 (2006.01); A61K 31/4745 (2006.01); A61K 31/704 (2006.01);
U.S. Cl.
CPC ...
A61K 31/24 (2013.01); A61K 31/335 (2013.01); A61K 31/4745 (2013.01); A61K 31/704 (2013.01);
Abstract
The present invention relates to combinations between artemisinin-based potent anti-malarial agents, selected from the group consisting of ART, DHA and ARM, and a further chemotherapeutic drug selected from the group consisting of a camptothecin derivative, or a PARP-1 inhibitor, or an intercalating DNA agent, or an alkylating agent. Such combinations, showed medium to strong synergism in various models of cancer, in particular in NSCL.