The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2015
Filed:
May. 13, 2013
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Michael B. Yaffe, West Roxbury, MA (US);
Isaac A. Manke, New York, NY (US);
Hans Christian Reinhardt, Cologne, DE;
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01); A61K 38/16 (2006.01); A61K 31/553 (2006.01); A61K 45/06 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C12N 9/12 (2006.01); C12Q 1/48 (2006.01); G01N 33/573 (2006.01); G01N 33/574 (2006.01); A61K 31/7034 (2006.01); A61K 33/24 (2006.01); G06F 19/16 (2011.01); G06F 19/20 (2011.01); G06F 19/22 (2011.01);
U.S. Cl.
CPC ...
A61K 31/553 (2013.01); A61K 31/00 (2013.01); A61K 38/16 (2013.01); A61K 45/06 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 2299/00 (2013.01); C12N 9/1205 (2013.01); C12Q 1/485 (2013.01); G01N 33/573 (2013.01); G01N 33/57407 (2013.01); G01N 2333/4748 (2013.01); G01N 2333/9121 (2013.01); G01N 2500/00 (2013.01); G01N 2500/02 (2013.01); G06F 19/16 (2013.01); G06F 19/20 (2013.01); G06F 19/22 (2013.01); A61K 31/7034 (2013.01); A61K 33/24 (2013.01);
Abstract
The present invention relates to compounds and pharmaceutical compositions for treating cellular proliferative disorders, e.g., in patients having one or more p53-deficient cells, screening assays for identifying such compounds, and methods for treating such disorders.