The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2015

Filed:

Jul. 26, 2006
Applicants:

Christian Hamon, Kriftel, DE;

Josef Schwarz, Frankfurt am Main, DE;

Wolfgang Becker, Eppstein, DE;

Stefan Kienle, Frankfurt am Main, DE;

Karsten Kuhn, Hofheim am Taunus, DE;

Juergen Schaefer, Lauterbach, DE;

Inventors:

Christian Hamon, Kriftel, DE;

Josef Schwarz, Frankfurt am Main, DE;

Wolfgang Becker, Eppstein, DE;

Stefan Kienle, Frankfurt am Main, DE;

Karsten Kuhn, Hofheim am Taunus, DE;

Juergen Schaefer, Lauterbach, DE;

Assignee:

Electrophoretics Limited, Cobham Surrey, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07D 401/12 (2006.01); C07D 239/04 (2006.01); C07D 403/12 (2006.01); C07D 207/404 (2006.01); C07K 5/078 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); G01N 2458/00 (2013.01); Y10T 436/24 (2015.01); C07D 207/404 (2013.01); C07D 401/12 (2013.01); C07K 5/06139 (2013.01); G01N 33/6848 (2013.01);
Abstract

A mass label for labelling and detecting a biological molecule by mass spectroscopy, which label comprises the following structure: X-L-M wherein X is a mass marker moiety comprising the following group: formula (I), wherein the cyclic unit is aromatic or aliphatic and comprises from 0-3 double bonds independently between any two adjacent atoms; each Z is independently N, N(R), C(R), CO, CO(R), C(R), O or S; X is N, C or C(R); each Ris independently H, a substituted or unsubstituted straight or branched C-Calkyl group, a substituted or unsubstituted aliphatic cyclic group, a substituted or unsubstituted aromatic group or a substituted or unsubstituted heterocyclic group; and y is an integer from 0-10, L is a cleavable linker comprising an amide bond and M is a mass normalization moiety.


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