The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2015

Filed:

Nov. 10, 2011
Applicants:

Stephen Poole, London, GB;

Mehul Patel, Lafayette, CO (US);

Inventors:

Stephen Poole, London, GB;

Mehul Patel, Lafayette, CO (US);

Assignees:

Baxter International Inc., Deerfield, IL (US);

Baxter Healthcare SA, Glattpark (Opfikon), CH;

The Secretary of State for Health, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); G01N 33/68 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6863 (2013.01); G01N 33/5047 (2013.01); G01N 33/5055 (2013.01); G01N 33/5091 (2013.01); G01N 33/6869 (2013.01);
Abstract

An improved monocyte activation test is described that is better able to detect non-endotoxin pyrogens in medical products, in which a sample is incubated with a monocyte-containing reagent in an assay system comprising at least one surface comprising polypropylene. The invention also concerns assay systems for use in these tests that include at least one microtiter well having at least one interior surface comprising polypropylene and having a shape such that monocyte-containing reagent is concentrated in the well to provide greater cell to cell contact. The invention also relates to a diagnostic kit that can be used to test for the presence of non-endotoxin pyrogens in a sample.


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