The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2015
Filed:
Feb. 05, 2010
Applicants:
John V. Frangioni, Wayland, MA (US);
Maged M. Henary, Lawrenceville, GA (US);
Inventors:
John V. Frangioni, Wayland, MA (US);
Maged M. Henary, Lawrenceville, GA (US);
Assignees:
Beth Israel Deaconess Medical Center, Boston, MA (US);
Georgia State University Research Foundation, Inc., Atlanta, GA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); C07D 209/02 (2006.01); A61K 49/00 (2006.01); C07D 255/02 (2006.01); A61B 6/00 (2006.01); C09B 23/01 (2006.01); C09B 23/08 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0032 (2013.01); C12Q 1/02 (2013.01); C07D 209/02 (2013.01); C07D 255/02 (2013.01); A61B 6/00 (2013.01); C09B 23/0066 (2013.01); C09B 23/086 (2013.01);
Abstract
The present invention relates to compositions and methods of optically imaging tissues or cells using imaging agents have in vivo properties that result in signal-to-background ratios of at least about 1:1. TL is a targeting ligand and n is −1, 0 or +1.