The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2015

Filed:

Mar. 14, 2008
Applicants:

Terrance Grant Johns, Heidelberg, AU;

Webster Cavenee, La Jolla, CA (US);

Frank Furnari, La Jolla, CA (US);

Andrew Scott, Heidelberg, AU;

Inventors:

Terrance Grant Johns, Heidelberg, AU;

Webster Cavenee, La Jolla, CA (US);

Frank Furnari, La Jolla, CA (US);

Andrew Scott, Heidelberg, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 14/71 (2006.01); A61K 31/517 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 39/39541 (2013.01); A61K 45/06 (2013.01); C07K 2317/30 (2013.01);
Abstract

The present invention relates to the treatment of EGFR-mediated disease, particularly cancer by inhibiting or blocking EGFR and src in combination or simultaneously. The invention relates to treatment, prevention, or modulation of cancer, particularly EGFR-mediated disease, with one or more EGFR modulator and src inhibitor in combination. The invention further relates to the treatment of cancer with anti-EGFR antibodies and src inhibitors. Methods and compositions for treatment of cancer with the antibody anti-EGFR mAb806 in combination or series with a src inhibitor or src inhibitors are described.


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