The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2015
Filed:
Mar. 25, 2013
Gang Chen, Rancho Palos Verdes, CA (US);
Umesh B. Gangadharmath, Los Angeles, CA (US);
Dhanalakshmi Kasi, Los Angeles, CA (US);
Harmuth C. Kolb, Playa Del Ray, CA (US);
Changhui Liu, Los Angeles, CA (US);
Anjana Sinha, San Diego, CA (US);
Anna Katrin Szardenings, Torrance, CA (US);
Joseph C. Walsh, Pacific Palisades, CA (US);
Eric Wang, San Diego, CA (US);
Chul Yu, Los Angeles, CA (US);
Wei Zhang, Los Angeles, CA (US);
Klaus Kopka, Muenster, DE;
Guenter Haufe, Muenster, DE;
Michael Schaefers, Havixbeck, DE;
Verena Hugenberg, Bersenbrueck, DE;
Stefan Wagner, Muenster, DE;
Sven Hermann, Muenster, DE;
Hans-joerg Breyholz, Muenster, DE;
Andreas Faust, Billerbeck, DE;
Gang Chen, Rancho Palos Verdes, CA (US);
Umesh B. Gangadharmath, Los Angeles, CA (US);
Dhanalakshmi Kasi, Los Angeles, CA (US);
Harmuth C. Kolb, Playa Del Ray, CA (US);
Changhui Liu, Los Angeles, CA (US);
Anjana Sinha, San Diego, CA (US);
Anna Katrin Szardenings, Torrance, CA (US);
Joseph C. Walsh, Pacific Palisades, CA (US);
Eric Wang, San Diego, CA (US);
Chul Yu, Los Angeles, CA (US);
Wei Zhang, Los Angeles, CA (US);
Klaus Kopka, Muenster, DE;
Guenter Haufe, Muenster, DE;
Michael Schaefers, Havixbeck, DE;
Verena Hugenberg, Bersenbrueck, DE;
Stefan Wagner, Muenster, DE;
Sven Hermann, Muenster, DE;
Hans-Joerg Breyholz, Muenster, DE;
Andreas Faust, Billerbeck, DE;
Siemens Medical Solutions USA, Inc., Malvern, PA (US);
Abstract
Novel compounds and pharmaceutical compositions having MMP inhibitory activity are disclosed, which have been found to be particularly useful in the prevention, treatment and diagnostic imaging of diseases associated with an unpaired activity of MMP, amongst others MMP-2, MMP-8, MMP-9 and/or MMP-13 to name a few. The compounds of the present invention are useful for the prevention, the treatment and the in vivo diagnostic imaging of a range of disease states (inflammatory, malignant and degenerative diseases) where specific matrix metalloproteinases are known to be involved.