The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2015

Filed:

Jan. 26, 2012
Applicants:

Michel Bouvier, Montreal, CA;

Anne Marinier, Kirkland, CA (US);

Réjean Ruel, Saint-Lambert, CA (US);

Patricia René, Montreal, CA;

Yves Chantigny, Pincourt, CA (US);

Philippe Dagneau, St-Laurent, CA (US);

Stéphane Gingras, Montreal, CA;

Inventors:

Michel Bouvier, Montreal, CA;

Anne Marinier, Kirkland, CA (US);

Réjean Ruel, Saint-Lambert, CA (US);

Patricia René, Montreal, CA;

Yves Chantigny, Pincourt, CA (US);

Philippe Dagneau, St-Laurent, CA (US);

Stéphane Gingras, Montreal, CA;

Assignee:

Université de Montréal, Montreal, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 231/56 (2006.01); C07D 487/00 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); G01N 33/74 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 487/04 (2013.01); G01N 33/74 (2013.01); G01N 2333/72 (2013.01); G01N 2500/04 (2013.01); G01N 2500/10 (2013.01); G01N 33/5008 (2013.01);
Abstract

Disclosed herein is a compound of Formula I: wherein X, R, R, and Rare as defend herein, or a pharmaceutically acceptable salt thereof to allow the drug to penetrate the cell membrane; or a prodrug, or the compound is labeled with a detectable label or an affinity tag thereof. Also disclosed is a pharmaceutical composition, a method of treating a disorder mediated by melanocortin-4 receptors, and a method of treating obesity using the compounds described.


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