The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2015

Filed:

Sep. 11, 2013
Applicant:

Jiangsu Simcere Pharmaceutical R&d Co., Ltd, Nanjing, CN;

Inventors:

Feng Tang, Nanjing, CN;

Qiu Jin, Nanjing, CN;

Wei Li, Nanjing, CN;

Tian Zhu, Nanjing, CN;

Yang Hu, Nanjing, CN;

Feng Shao, Nanjing, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4045 (2006.01); C07D 209/42 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4045 (2013.01); C07D 209/42 (2013.01);
Abstract

Provided are acid addition salts of (Z)—N-[2-(diethylamino)ethyl]-2-methyl-7-(1,2 -dihydro-5-fluoro-2-oxo-3H-indol-3-ylidene)-4,5,6,7-tetrahydro-1H-indol-3-carboxamide, wherein the salt comprising at least one of a number of salts including L-malate, hydrochloride, phosphate, L-tartrate, benzenesulfonate, sulfate, methanesulfonate, succinate, citrate, fumarate, p-toluenesulfonate, hydrobromate, L-mandelate, lactate, acetate or maleate salt. Also provided is a pharmaceutical composition comprising the salt compounds, and a method of treatment by administering a therapeutically effective amount of the salt compounds as preparation of medicaments.


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