The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2015

Filed:

Nov. 08, 2010
Applicants:

Alexandros Vakalopoulos, Hilden, DE;

Martin Michels, Köln, DE;

Katja Zimmermann, Düsseldorf, DE;

Nicole Teusch, Wülfrath, DE;

Mario Lobell, Wuppertal, DE;

Karen Engel, Wuppertal, DE;

Inventors:

Alexandros Vakalopoulos, Hilden, DE;

Martin Michels, Köln, DE;

Katja Zimmermann, Düsseldorf, DE;

Nicole Teusch, Wülfrath, DE;

Mario Lobell, Wuppertal, DE;

Karen Engel, Wuppertal, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/40 (2006.01); A61K 31/44 (2006.01); C07D 211/02 (2006.01); C07D 401/00 (2006.01); C07D 413/14 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01);
Abstract

The present invention relates to novel, fluoro-substituted 2-aryl-3,5-dicyano-4-(1H-indazol-5-yl)-6-methyl-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly Cancer and other proliferative disorders.


Find Patent Forward Citations

Loading…